The goal of this brief is to provide research-based information on trauma-informed care (TIC) with young children, with a focus on young children in low-income families. This brief provides educators, administrators, and policymakers with information about the challenges faced by young children from low-income families in general and during COVID-19. It then provides an overview of TIC for those working in settings that reach such children, including home visiting and early childhood education and care. (author abstract)